HHCH: Structure, effects, risks and intergalactic comparison with THCJD and THCB

What is HHCH and what is its chemical structure?

HHCH or hexahydrocannabihexol is a semi-synthetic derivative of cannabinoid, we would look for it in vain in the cannabis plant, it is produced only in a laboratory environment.

Scientists convert THCH (tetrahydrocannabichetol) distillate through a process called hydrogenation. This process can be likened to the birth of a supernova from a star. Hydrogenation sets off a chain reaction that transforms the THCH distillate into a new form, which is then converted into HHCH to produce a thick, high-viscosity oil.

The high viscosity means that the oil is extremely thick and sticky. This means the degree of internal friction of the fluid, which affects how easily the fluid flows. It can be imagined that the oil flows slowly and is not as fluid, like honey or thick syrup.

This property makes it an ideal substance for vape cartridges, as the liquid needs to stay in place around the heating element without draining or dripping too quickly.

Moving back a few decades, we find that as early as 1942 the first synthesis of HHCH was made by the eminent American chemist Roger Adams, who was also the first to isolate pure CBD from Cannabis sativa. In his scientific study, Roger Adams stated that HHCH was more potent than the pentyl and heptyl homologues or the unsaturated analogue THC (tetrahydrocannabinol).

The molecular formula of HHCH is C22H34O2. Since it is a hydrogenated compound, like H4CBD and HHC, it consists of 2 stereoisomers: 9(R)-HHCH and 9(S)-HHCH.

In the galactic archive we have a study on HHC from 2023 which states that the 9(R) molecule binds more efficiently to CB1 receptors in the endocannabinoid system, producing a psychoactive effect, whereas 9(S) is thought to be more of an inactive component.


Cannabinoid receptors are divided into 2 main subtypes, referred to as CB1 and CB2, medical and medical cannabis illustrations.

Astral effects of HHCH

The effects of HHCH are similar to those of THC. There is also speculation that it may be about 10-15 times more potent than THC and that it is more potent than THCH. The effects of HHCH seem to be like a comet whizzing through the atmosphere with tremendous energy. However, there is no research in the galactic archive to confirm this hypothesis.

There is information on planet Earth that the effects are slightly milder and last longer compared to the cannabinoid HHCP. HHC can take effect for 2-8 hours.

And because it is a compound with psychoactive properties, like THCB, THCJD, THCP, THCPO and HHC, it can affect perception, inducing feelings of euphoria or relaxation.

HHCH products are exclusively suited for experienced astronauts, as semi-synthetic cannabinoids can be much more potent than natural cannabinoids. Under no circumstances should HHCH be tested before operating a spacecraft or other craft.

Galactic Alert: Watch out for side effects

Semisynthetic compounds can act with supernova-like intensity in the body, increasing the potential risk of negative psychoactive effects, intoxication and overdose, which can result in a "bad trip" that can be as turbulent, chaotic and challenging as passing through a dangerous asteroid field.

Astronauts may feel disoriented, and negative side effects such as paranoia, anxiety, panic and hallucinations may occur.

Other possible side effects include:

  • Redness of the eyes
  • Dry mouth
  • Fatigue and drowsiness
  • Increased heart rate
  • Nausea (vomiting)
  • Headache

At the moment, it cannot be ruled out that other, as yet undetected, side effects of HHCH will not appear in the future, because, as with the discovery of new exoplanets, scientists may find unprecedented and unexpected phenomena.

Of course, the effects mentioned always depend on several factors, including the method of consumption, dose size, sensitivity and metabolism of the individual explorer.

Warning: pass through the zone of (semi)synthetic cannabinoids

When it comes to how to safely navigate the cannabinoid universe without falling into a black hole, the golden rule applies: "When purchasing any cannabis products, always request a third-party lab analysis and approach use responsibly."

In the analyses you will find objective data on product purity, compliance with the legal codes of planet Earth (maximum permissible THC limit), safety and more. Ensure that the product is free of unsuitable additives, fillers and toxins.

The legal vacuum in which most semi-synthetic cannabinoids currently find themselves is comparable to the far reaches of space, where no space treaties or regulations apply, and this makes it difficult overall to ensure the safety of cannabis products on planet Earth.

Always rely on trusted and proven companies that have their products tested.


Minimalist illustration showing the use of the cannabinoid CBD while flying

Intergalactic comparison of HHCH, THCJD and THCB




Other names

  • Hexahydrocannabihexol
  • Tetrahydro-cannabidiol
  • THC-JD, THCjd
  • THC-Octyl
  • delta 8-THC-C8
  • JWH-138
  • Δ9-Tetrahydrocannabinol-C8
  • Tetrahydro-cannabutol
  • THC-B, THCb
  • nor-THC
  • Δ9-Tetrahydrocannabinol-C4
  • Δ9-THC-butyl
  • Δ9-THC-C4

Natural vs. synthetic cannabinoid

Not found in cannabis, a semi-synthetic cannabinoid derivative, it is formed by hydrogenation of THCH distillate and its conversion to HHCH.

It is reportedly found in trace amounts in the cannabis plant, but is mostly made from other cannabinoids (CBD).

It occurs naturally in cannabis, but only in low abundance, and is more commonly produced from other cannabinoids (CBD).

Molecular formula





Hydrogenated compound, consists of 2 stereoisomers: 9(R)-HHCH and 9(S)-HHCH.

The homologue of the cannabinoid THC, THCJD has an alkyl side chain with 8 carbons.

The cannabinoid homologue of THC, THCB has a butyl chain with 4 carbons.

Psychoactive effects




Side effects

  • Redness of the eyes
  • Dry mouth
  • Fatigue and drowsiness
  • Increased heart rate
  • Nausea (vomiting)
  • Headache
  • Negative psychological effects such as paranoia, anxiety, hallucinations and panic
  • Dry mouth
  • Redness of the eyes
  • Impaired coordination
  • Increased heart rate
  • Memory problems
  • Negative psychological effects such as paranoia, anxiety, hallucinations and panic
  • Dry mouth
  • Redness of the eyes
  • Impaired coordination
  • Increased heart rate
  • Memory problems
  • Dizziness
  • Lethargy
  • Negative psychological effects such as paranoia, anxiety, hallucinations and panic

Available products

  • HHCH vapes, replacement cartridges and liquids
  • HHCH oil
  • Extracts and concentrates
  • HHCH Distillate
  • Flowers (flowers of technical hemp infused with HHCH distillate)
  • Hash
  • THCJD vape pens, cartridges and liquids
  • Gummies and candies
  • Edibles
  • Tinctures
  • Hash
  • THCJD distillate
  • Flowers
  • THCJD oils and drops
  • Extracts and concentrates
  • THCB vape pens, replacement cartridges and liquids
  • Distillates
  • Flowers
  • Gummies
  • Hash

Legal status

It is defined as legal under the Farm Bill, but may be in the grey legal area in some states or already on the banned substances list.

As of 1 May 2024, it is not on the list of banned substances in most countries.

As of 1 May 2024, it is not on the list of banned substances in most countries.


Final modulation

Hexahydrocannabihexol is a semi-synthetic cannabinoid derivative that is produced in the laboratory by a hydrogenation process. This process transforms the original structure of THCH into a new form. The final form of HHCH is a thick, high-viscosity oil consisting of 2 distinct stereoisomers: 9(R)-HHCH and 9(S)-HHCH. These molecules are like a pair of planets in one orbital system, the ratio of which determines the overall efficiency and strength of the product. If 9(R) predominates in the product, the product will be more potent.

The International Space Station warns that (semi)synthetic cannabinoids have a much higher potential risk of unpleasant psychoactive effects, intoxication and overdose than natural ones.

One of the other risks of similar substances is that they may be contaminated with undesirable substances (heavy metals, pesticides or solvents). Therefore, always choose verified companies that have their products tested by a third party. This will minimize the risk of buying a poor quality or even unsafe product.

Based on reports to date, the effects of HHCH are thought to be similar to those of THC, and there are reports that it is estimated to be 10-15 times more potent than THC and that it is superior to THCH in its effects. HHCH is recommended for experienced astronauts.

Still, the International Space Laboratories are only at the starting line of research and the galactic archive lacks research to evaluate the effects and safety of this substance.

Anyone who decides to experiment with substances of this type should always consider all the risks. Space exploration must be approached responsibly and with respect, and not try to go beyond gravity.


Author: Cannastra 🚀



Photo: Shutterstock

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